After careful consideration, the choice was a Moots titanium Baxter frameset equipped with an Enve G27 wheelset, gravel bars, stems, seatpost, Maxxis 27.5 x 2.35 IKON tires, and Shimano Di2 shifting.
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Understandably, this seems like a doctor's dream bike, and it is, but the titanium was the perfect material to withstand the sand, rock, dirt, water, salt, and other elements which were thrown at it during the expedition. The newly designed ENVE G27 gave the Maxxis tires a slightly wider stance and, with nearly zero chance of pinch flat, the riders were able to ride 20 lbs of pressure the entire way without losing a single pound of pressure.